School of Biosciences and Bioengineering
Indian Institute of Technology Mandi
Research
Exploring the applications of nanomaterials in Life Sciences
Metal Nanostructures
J. Phys. Chem. C, 2017
We are working on the preparation of different metal nanostructures adorned with the properties of intrinsic EM hotspots and absorbance in the NIR region. These properties enable SERS based bioimaging, stimuli responsive drug release and photothermal therapy.
2D Materials
2D MoS2 nanosheets
We are putting efforts to exfoliate different 2D materials using polymers/biomolecules and prepare its nanocomposite for biomedical applications. Some of the 2D materials e.g. reduced graphene oxide and MoS2 exhibit absorbance in the NIR region which enable photothermal therapy.
Nanomedicine
Nanomedicine, 2019
In an effort to achieve stimuli responsive therapy and targeted drug delivery, we work on the fabrication of different metal/2D nanomaterial based polymeric nanocomposite and use it as a nanocarriers for delivering therapeutic molecules to cancer cells. We also try to understand the mechanism of cell death involved while using the prepared nanomedicine.
Sensors
Gold nanocapsule deposited cellulose substrate for SERS
We are also working towards the fabrication of flexible sensors for the detection of trace analyte molecules. The sensing mechanism either involves surface enhanced Raman scattering (SERS) or plasmonics. A major advantage of this development is its improved sensitivity, which allows it to detect analyte molecules down to picomolar concentration.
Antimicrobials/ Wound Healing
ACS Appl. Bio Mater. 2019
Antibiotic resistance amongst bacteria is a major concern. We are exploring the antibacterial potential of 2D materials and different polymers and its composites. We also put our effort to understand the mechanism of antibacterial action using these nanocomposites.
Environmental Remediation
J. Phys. Chem. C, 2017
We are exploring the potential of the metal nanostructures and 2D materials for degradation of environmental pollutants and adsorption of heavy metals and organic dyes. We are working towards the preparation or hydrogels reinforced with different nanomaterials to be used as a reusable material for environmental remediation.
Our Research is supported by:
